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Letter to the editors regarding “The conundrum of the PFOA human half-life,...
Campbell et al. (2022) propose that many studies estimating the human half-life of perfluorooctanoic acid (PFOA) are significantly confounded by lack of accounting for ongoing... -
Legacy and emerging per- and polyfluoroalkyl substances suppress the...
Per- and polyfluoroalkyl substances (PFASs) are used in a multitude of processes and products, including nonstick coatings, food wrappers, and fire-fighting foams. These... -
Information Requirements under the Essential-Use Concept: PFAS Case Studies
Per- and polyfluoroalkyl substances (PFAS) are a class of substances for which there are widespread concerns about their extreme persistence in combination with toxic effects.... -
Immunotoxicity of an Electrochemically Fluorinated Aqueous Film-Forming Foam
Aqueous film-forming foams (AFFFs) are complex per- and polyfluoroalkyl substance (PFAS)-containing mixtures used extensively as fire suppressants. AFFF-impacted groundwater and... -
Finding essentiality feasible: common questions and misinterpretations...
The essential-use concept is a tool that can guide the phase-out of per- and polyfluoroalkyl substances (PFAS) and potentially other substances of concern. This concept is a... -
Exposure to per-fluoroalkyl and polyfluoroalkyl substances leads to...
In this perspective, we evaluate key and emerging epidemiological and toxicological data concerning immunotoxicity of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate... -
Emerging toxicological awareness of per- and polyfluoroalkyl substances: the...
Per- and polyfluoroalkyl substances (PFAS) are often called ‘forever chemicals’. This colloquialism reflects that many PFAS are recalcitrant to environmental and metabolic... -
Cross-sectional associations between serum PFASs and inflammatory biomarkers...
Background Per- and polyfluoroalkyl substances (PFASs) are widespread and persistent environmental contaminants. Exposure to several PFASs has been associated with altered... -
Are Fluoropolymers Really of Low Concern for Human and Environmental Health...
Fluoropolymers are a group of polymers within the class of per- and polyfluoroalkyl substances (PFAS). The objective of this analysis is to evaluate the evidence regarding the... -
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
Per- and polyfluoroalkyl substances (PFAS) are of concern because of their high persistence (or that of their degradation products) and their impacts on human and environmental... -
A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?
More than 3000 per- and polyfluoroalkyl substances (PFASs) are, or have been, on the global market, yet most research and regulation continues to focus on a limited selection of... -
Addressing Urgent Questions for PFAS in the 21st Century
Despite decades of research on per- and polyfluoroalkyl substances (PFAS), fundamental obstacles remain to addressing worldwide contamination by these chemicals and their...