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PFOS dominates PFAS composition in ambient fine particulate matter...
Contamination of drinking water by per- and polyfluoroalkyl substances (PFASs) emitted from manufacturing plants, fire-fighting foams, and urban waste streams has received... -
Quantifying the impact of PFOA exposure on B-cell development and antibody production
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals; the vast majority are environmentally and biologically persistent, and some have demonstrated toxicity,... -
Immunotoxicity of Per- and Polyfluoroalkyl Substances: Insights into...
Novel per- and polyfluoroalkyl substances (PFAS) were recently identified in drinking water sources throughout North Carolina. These include the perfluoroether acids (PFEAs)... -
Recently Detected Drinking Water Contaminants: GenX and Other Per‐ and...
For several decades, a common processing aid in the production of fluoropolymers was the ammonium salt of perfluorooctanoic acid (PFOA). Because PFOA is persistent,... -
Recently Detected Drinking Water Contaminants: GenX and Other Per- and...
For several decades, a common processing aid in the production of fluoropolymers was the ammonium salt of perfluorooctanoic acid (PFOA). Because PFOA is persistent,... -
Scientific Basis for Managing PFAS as a Chemical Class
This commentary presents a scientific basis for managing as one chemical class the thousands of chemicals known as PFAS (per- and polyfluoroalkyl substances). The class includes... -
Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults...
BACKGROUND: From 1980 to 2017, a fluorochemical manufacturing facility discharged wastewater containing poorly understood per- and polyfluoroalkyl substances (PFAS) to the Cape... -
Factors associated with per- and polyfluoroalkyl substances (PFAS) serum...
In 2017, people living in New Hanover County, North Carolina, learned that for ∼40 years they were unknowingly exposed to per- and polyfluoroalkyl substances (PFAS) through... -
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated...
To estimate half-lives for novel fluoroethers, the GenX Exposure Study obtained two serum measurements for perand polyfluoroalkyl substances (PFAS) for 44 participants of age... -
Bioaccumulation of Novel Per- and Polyfluoroalkyl Substances in Mice Dosed...
Per- and polyfluoroalkyl substances (PFASs) are widespread in the blood of the general human population, and their bioaccumulation is of considerable scientific and regulatory... -
Zürich Statement on Future Actions on Per- and Polyfluoroalkyl Substances (PFASs)
Per- and polyfluoroalkyl substances (PFASs) are man-made chemicals that contain at least one perfluoroalkyl moiety, –CnF2n–. To date, over 4,000 unique PFASs have been used in... -
Widening the Lens on PFASs: Direct Human Exposure to Perfluoroalkyl Acid...
Determining health risks associated with per-/polyfluoroalkyl substances (PFASs) is a highly complex problem requiring massive efforts for scientists, risk assessors, and... -
Using Chicken Embryo as a Powerful Tool in Assessment of Developmental...
Chicken embryos are a classical model in developmental studies. During the development of chicken embryos, the time window of heart development is welldefined, and it is... -
The high persistence of PFAS is sufficient for their management as a chemical class
Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic organic substances with diverse structures, properties, uses, bioaccumulation potentials and toxicities.... -
The concept of essential use for determining when uses of PFASs can be phased out
Because of the extreme persistence of per- and polyfluoroalkyl substances (PFASs) and their associated risks, the Madrid Statement argues for stopping their use where they are... -
Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to...
Grouping strategies are needed for per- and polyfluoroalkyl substances (PFAS), in part, because it would be time and resource intensive to test and evaluate the more than 4700... -
Scientists’ Statement on the Chemical Definition of PFASs
The undersigned are scientists with expertise in per- and polyfluoroalkyl substances (PFASs) and/or the management of chemicals. We assert that the Organization for Economic Co-... -
Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current...
Reports of environmental and human health impacts of per- and polyfluoroalkyl substances (PFAS) have greatly increased in the peer-reviewed literature. The goals of the present... -
Per- and Polyfluoroalkyl Substances (PFAS) Enhance Cholesterol Accumulation...
Epidemiological studies and in vivo animal models have shown that exposure to PFAS can lead to cardiovascular toxicity and promote atherosclerosis. In this study, we explored... -
Per- and polyfluoroalkyl substances alter innate immune function: evidence...
Per- and polyfluoroalkyl substances (PFASs) are a large class of compounds used in a variety of processes and consumer products. Their unique chemical properties make them...